Reflecting state-of-the-art developments, Microfluidic Lab-on-a-Chip for Chemical and Biological Analysis and Discovery reviews basic principles of micromachining as well as fluid flow and control, placing emphasis on analytical applications of microfluidic technology. This book covers micromachining methods, microfluidic operations, chemical separation, detection technology, and various chemical and biochemical analyses. The text is accessible for readers new to the field but also features various references for experienced researchers. It also adapts principles of operations on the chip, resulting in the miniaturization advantage and enhanced effects due to favorable scaling down.